How to Use 5 Blood Products from Whole Blood

Every 2 seconds a blood transfusion is needed in the United States. Let me walk you through what you need to know about how we derive and how we use blood products. We give transfusions as a way to supplement blood loss, maintain hemostasis and oxygenation in a wide range of scenarios: major blood lossContinue reading “How to Use 5 Blood Products from Whole Blood”

Everything You Need to Know: Dabigatran

Dabigatran changed the landscape and set a new standard for oral anticoagulation in 2010. It was the first oral alternative to warfarin and the inaugural member of the drug class Direct Acting Oral Anticoagulants (DOACs). It is still the only oral anticoagulant in the subclass of Direct Thrombin Inhibitor. Let me walk you through everythingContinue reading “Everything You Need to Know: Dabigatran”

Rivaroxaban: What You Need to Know to Maximize Patient Outcomes

2 million people use rivaroxaban each year. The benefits are proven, the risks are manageable. Let me what you through what you need to know to minimize risk and optimize efficacy. Rivaroxaban is an oral anticoagulant. It belongs to the drug class: Direct Oral Anticoagulant (DOAC). DOACs were introduced in 2010 as an alternative toContinue reading “Rivaroxaban: What You Need to Know to Maximize Patient Outcomes”

Everything You Need to Know: Apixaban

Apixaban is an oral anticoagulant. It belongs to the drug class: Direct Oral Anticoagulant (DOAC). DOACs were introduced in 2010 as an alternative to warfarin. They address alot of the complexities associated with the use of warfarin. Warfarin is effective within a very narrow therapeutic range. This window of efficacy is easily disrupted by manyContinue reading “Everything You Need to Know: Apixaban”

Fundamentals of Warfarin Dosing

Efficacy of warfarin is determined by the attain and maintaining an INR (International Normalized Ratio) with a narrow range of usually 2-3. This requires consistent blood monitoring. INR is essentially a measure of how quickly blood will clot. The unit Warfarin: The Fundamentals discusses the mechanism of action and drug interactions of warfarin in moreContinue reading “Fundamentals of Warfarin Dosing”