Dabigatran changed the landscape and set a new standard for oral anticoagulation in 2010. It was the first oral alternative to warfarin and the inaugural member of the drug class Direct Acting Oral Anticoagulants (DOACs). It is still the only oral anticoagulant in the subclass of Direct Thrombin Inhibitor. Let me walk you through everythingContinue reading “Everything You Need to Know: Dabigatran”
Tag Archives: anticoagulation
Everything You Need to Know: Apixaban
Apixaban is an oral anticoagulant. It belongs to the drug class: Direct Oral Anticoagulant (DOAC). DOACs were introduced in 2010 as an alternative to warfarin. They address alot of the complexities associated with the use of warfarin. Warfarin is effective within a very narrow therapeutic range. This window of efficacy is easily disrupted by manyContinue reading “Everything You Need to Know: Apixaban”
Fundamentals of Warfarin Dosing
Efficacy of warfarin is determined by the attain and maintaining an INR (International Normalized Ratio) with a narrow range of usually 2-3. This requires consistent blood monitoring. INR is essentially a measure of how quickly blood will clot. The unit Warfarin: The Fundamentals discusses the mechanism of action and drug interactions of warfarin in moreContinue reading “Fundamentals of Warfarin Dosing”
How to Treat: Atrial Fibrillation
Treatment of atrial fibrillation centers reducing the risk of thrombus formation and stroke as well as treatment as disease progresses. Learn how we use validated tools to balance risk of the atrial fibrillation with the risk of treatment.