Warfarin, the traditional anticoagulant, has drawbacks such as narrow therapeutic range and frequent monitoring. Direct Oral Anticoagulants (DOAC) address these limitations. DOACs directly inhibit clotting factors, unlike warfarin which indirectly inhibits them. They are preferred due to easier administration, fewer interactions, and superior efficacy. Dabigatran, rivaroxaban, apixaban, and edoxaban are the available DOACs, each with unique attributes and considerations for administration and interactions.
Tag Archives: atrial fibrillation
Everything You Need to Know: Dabigatran
Dabigatran changed the landscape and set a new standard for oral anticoagulation in 2010. It was the first oral alternative to warfarin and the inaugural member of the drug class Direct Acting Oral Anticoagulants (DOACs). It is still the only oral anticoagulant in the subclass of Direct Thrombin Inhibitor. Let me walk you through everythingContinue reading “Everything You Need to Know: Dabigatran”
How to Treat: Atrial Fibrillation
Treatment of atrial fibrillation centers reducing the risk of thrombus formation and stroke as well as treatment as disease progresses. Learn how we use validated tools to balance risk of the atrial fibrillation with the risk of treatment.
Atrial Fibrillation: Symptoms, Causes and How to Treat
Atrial fibrillation (AF) is a disorder of how your heart generates and conducts the electrical signals needed for cardiac muscle contractions. Coordination of impulse generation, impulse conduction and muscle contraction is what maintains normal sinus rhythm.